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Modifying Neural Stem Cells Improves Their Therapeutic Efficacy

Stem cells isolated from the brain of adult mice (adult neural stem cells [aNSCs]) have shown very modest therapeutic effects in a mouse model of the chronic inflammatory neurodegenerative disease multiple sclerosis.

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Glial cells can cross from the central to the peripheral nervous system

Glial cells, which help neurons communicate with each other, can leave the central nervous system and cross into the peripheral nervous system to compensate for missing cells,

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Early protein processes crucial to formation and layering of myelin membrane

New findings from an international team of researchers probing the nerve-insulating myelin sheath were bolstered by the work of Boston College biologists, who used x-rays to uncover how mutations affect the structure of myelin, a focal point of research in multiple sclerosis and other neurological disorders.

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Factors from common human bacteria may trigger multiple sclerosis

Current research suggests that a common oral bacterium may exacerbate autoimmune disease.

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Multiple sclerosis is more aggressive in children but slower to cause disability than in adults

ms

ScienceDaily (Nov. 23, 2009) - Magnetic resonance images (MRI) of patients diagnosed with multiple sclerosis in childhood show that pediatric onset multiple sclerosis is more aggressive, and causes more brain lesions, than MS diagnosed in adulthood, researchers at the University at Buffalo have reported.

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